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It is impotant tinstuct patints tadh tditay instuctions and thav blood glucos and glycosylatd hmoglobin tstd gulaly. Duing piods stss such as v, tauma, inction, sugy, mdication quimnts may chang and patints should b mindd tsk mdical advic pomptly. Tll patints tpomptly pot any sign macoscopichmatuia oth symptoms such as dysuia uinay ugncy that dvlop incas duing tatmnt as ths may b du tbladd canc. xplain tpatints th isks lactic acidosis, its symptoms and conditions that pdispos tits dvlopmnt, as notd in th WANINGS AND PCAUTIONS sction. Advis patints tdiscontinu ACTOPLUS MT immdiatly and tpomptly notiy thi halthca possional i unxplaind hypvntilation, myalgia, gastointstinal symptoms, malais, unusual somnolnc, oth nonspciic symptoms occu. Counsl patints against xcssiv alcohol intak whil civing ACTOPLUS MT. Inom patints timmdiatly pot symptoms an unusually apid incas in wight dma, shotnss bath, oth symptoms hat ailu whil civing ACTOPLUS MT. Tll patints tpomptly stop taking ACTOPLUS MT and sk immdiat mdical advic i th is unxplaind nausa, vomiting, abdominal pain, atigu, anoxia, dak uin as ths symptoms may b du thpatotoxicity. Inom patints about th impotanc gula tsting nal unction and hmatologic paamts whn civing tatmnt with ACTOPLUS MT. Inom patints that thapy with a thiazolidindion, which is th activ pioglitazon componnt th ACTOPLUS MT tablt, may sult in ovulation in som pmnopausal anovulatoy womn. As a sult, ths patints may b at an incasd isk pgnancy whil taking ACTOPLUS MT. commnd adquat contacption all pmnopausal womn wha pscibd ACTOPLUS MT. Patints should b advisd tnotiy thi halth pactition call th Poison Contol Cnt immdiatly in cas ACTOPLUS MT ovdos. Combination antihypglycmic thapy may caus hypoglycmia. Whn initiating ACTOPLUS MT, th isks hypoglycmia, its symptoms and tatmnt, and conditions that pdispos tits dvlopmnt should b xplaind tpatints and thi amily mmbs. Patints should b told ttak ACTOPLUS MT as pscibd and instuctd that any chang in dosing should only b don i dictd by thi physician. I a dos is missd on on day, th dos should not b doubld th ollowing day.

This mdication can caus changs in th mnstual cycl (pomot ovulation) and incas th isk bcoming pgnant. Consult you doctphamacist about th us liabl bith contol whil using this mdication.

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